BDBM588264 1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6- (1H-pyrrol-2- yl)quinolin-4- yl]oxyphenyl]cyclopropane- 1,1-dicarboxamide::US11542259, Compound 188
SMILES COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1-c1ccc[nH]1
InChI Key InChIKey=KFWMNBSUTXQRCO-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 588264
TargetHepatocyte growth factor receptor MET Isoform 2 [974-1390,A1209G,V1290L](Homo sapiens (Human))
Exelixis
US Patent
Exelixis
US Patent
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
Ligand Info